It would appear that Paul, after being placed under house-arrest for two years in Rome (Acts 28), was later allowed to make another missionary journey under some level of supervision. This journey would have taken place between AD 63 and 65. We gather that this journey took place because of the persons and places mentioned in Titus and 2 Timothy, and also from statements as in Philemon v.22, where Paul, writing from prison in Rome, tells Philemon, "prepare me also a lodging". We know from the greetings of Colossians, Philemon, and Philippians that Timothy was with Paul when those epistles were written from Rome. At some point Timothy himself was imprisoned, and Paul mentions his release in Heb. 13:23, and indicated that he would make a journey with Timothy; "if he should come soon, I will see you". Nevertheless, God chose that the book of Acts should conclude where it did, and if Luke wrote a third letter to Theophilus it is unknown. A detailed description of one or more subsequent missionary journeys was not included in the canon of holy scripture.